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If both mice have the same strange left-click issues, there’s definitely a software issue with your PC. There could also be a problem with a USB port on your system—if it’s a wired mouse, try plugging your mouse into another USB port. The mouse button may work great much of the time and only fail sometimes.
How do I reset my mouse buttons?
To reset a computer mouse:
- Unplug the mouse.
- With the mouse unplugged, hold down the left and right mouse buttons.
- While holding down the mouse buttons, plug the mouse back into the computer.
- After around 5 seconds, release the buttons. You will see an LED flash if it resets successfully.
More Information
- Click Start, and then click Control Panel.
- Double-click Mouse.
- Click the Buttons tab.
- Under Button Assignment, click the box for a button to which you want to assign a function, and then click the function that you want to assign to that button.
- Click Apply, and then click OK.
- Close Control Panel.
How to fix mouse unresponsive in Windows 10?
Check Mouse Properties Open Settings > Devices > Mouse > Additional mouse options. Mouse Properties will open. Click on Buttons tab. Check Turn on Click Lock option and click Apply. Then uncheck this option and click Apply again. See if it has helped. Run DISM tool DISM tool is another command-line tool available in Windows computer.
Mouse left and right click buttons unresponsive for periods of time seemly at random. Mouse tried: wired, wireless, wireless, Bluetooth, surface typecover cover touchpad and all possible combinations at the same time. Left and right click will be locked for periods of time. Persists through restarts.
What to do when your mouse stops responding?
Mouse stops responding during normal usage or after wake from sleep 1 Open Control Panel. 2 Open Devices and Printers. 3 Click Add Device.
The easiest solution is to use a free program called X-Mouse Button Control. Autohotkey script to disable ‘Button 4’ should also work well. Go to Device Manager, find the corresponding mouse name, right click on it, select Disable device and then Enable device. Update or reinstall the mouse driver.