How do you reference HGNC?

How do you reference HGNC?

To cite data within the database use the following format: HGNC Database, HUGO Gene Nomenclature Committee (HGNC), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom www.genenames.org.

What is an Official gene symbol?

A gene symbol is a short-form abbreviation for a particular gene. Gene nomenclature rules were established by the Nomenclature Committee of the Human Genome Organisation (HUGO) and were later adopted by other species-specific research communities.

How do you read gene names?

Nomenclature generally follows the conventions of human nomenclature. Gene symbols generally are italicised, with all letters in uppercase (e.g., NLGN1, for neuroligin1). Protein designations are the same as the gene symbol, but are not italicised; all letters are in uppercase (NLGN1).

How do you write genes and proteins?

General rules:

  1. Full gene names are italicized, all lower case, NEVER use Greek symbols. eg: cyclops (in italics)
  2. Gene symbols are italicized, all lower case. eg: cyc (in italics)
  3. Protein designations are the same as the gene symbol, but first letter only upper case and not italicized. eg: Cyc.

How do you write genes for mice?

Mice and rats: Gene symbols are italicized, with only the first letter in upper-case (e.g., Gfap). Protein symbols are not italicized, and all letters are in upper-case (e.g., GFAP). Fish: In contrast to the general rule, full gene names are italicized (e.g., brass).

What are the HGNC guidelines for protein nomenclature?

For protein nomenclature, please see the International Protein Nomenclature Guidelines, which were written with the involvement of the HGNC. In agreement with these guidelines, we recommend that “protein and gene symbols should use the same abbreviation”, with proteins using non-italicised symbols to differentiate them from genes.

Are there any exceptions to the HGNC guidelines?

Historically, the HGNC has only approved symbols for genes that are on the human reference genome. Rare exceptions have been made when requested by particular communities with dedicated nomenclature committees, such as the HLA community.

Where can I find the HUGO gene symbols?

We have a list of Affymetrix hgu133plus2 identifiers and we would like to retrieve the HUGO gene symbols, chromosome names, start and end positions and the bands of the corresponding genes.

How are lncRNAs assigned to protein coding genes?

LncRNAs that are intergenic with respect to protein coding genes are assigned the root symbol – LINC# followed by a 5‐digit number e.g. LINC01018 LncRNAs that are antisense to the genomic span of a protein coding gene are assigned the symbol format [protein coding gene symbol]‐AS# e.g. FAS-AS1