What is the difference between id and AC number in swissprot entry?
Accession numbers are stable from release to release. If several UniProtKB entries are merged into one, for reasons of minimizing redundancy, the accession numbers of all relevant entries are kept. However, an accession number (AC) is always conserved, and therefore allows unambiguous citation of UniProt entries.
How do I retrieve data from Uniprot?
Retrieving sequences from the website
- Perform your favorite query and view the resulting list of entries (e.g. this query retrieves all UniProtKB entries that are part of the human proteome: proteome:UP000005640)
- Click the Download button in the query result page.
How to convert gene symbols to UniProtKB identifiers?
You can upload your list of UniProtKB identifiers (AC or ID) to the batch retrieval service (“Retrieve/ID mapping”). Then click on the link “UniProtKB (xx)” (“xx” being the number of entries in your result) and then on “Columns” to hide all columns except gene names.
How does UniProt do Geneid and RefSeq mappings?
How does UniProt do GeneID and RefSeq mappings? As per a protocol we have formalized with the NCBI, we create a RefSeq protein-centric mapping. If a UniProtKB protein (canonical or isoform sequence) then that RefSeq accession is mapped to the UniProtKB protein and consequently the entry will also get the corresponding GeneID cross-reference.
How to upload a list of UniProt identifiers?
Convert identifiers which are of a different type to UniProt identifiers or vice versa, and download the identifier lists. Enter identifiers or upload them from a file, separated by a space or a new line, into the form field, for example: P31946 P62258 ALBU_HUMAN
How are sequence database identifiers mapped to UniProtKB?
When mapping popular sequence database identifiers such as RefSeq, gi numbers, EMBL, EMBLCDS to UniProtKB, unmapped identifiers can be further mapped to UniParc. This can be particularly useful for proteins from redundant proteomes. Very large mapping requests (>50,000 identifiers) are likely to fail.